Endocrine Abstracts

Introduction: Aim of this study was to assess the prevalence of subclinical hypothyroidism in a paediatric population of overweight and obese children and its association with metabolic parameters and with metabolic syndrome (MS).Subjects and methods: Clinical and metabolic evaluations in 600 overweight and obese children and adolescents (310 females, 290 males, 260 prepubertal, 240 pubertal, mean age: 10.7±3.1 years) were performed. MS was defined ...

Introduction: Vitamin D plays an important role on musculoskeletal composition, but new evidences highlight others possible pleiotropic effects on many tissues and also metabolic functions. Vitamin D insufficiency should be associated with all-cause mortality, in particular with cardiovascular disease and metabolic syndrome. International studies suggested that 25(OH)D level sufficiency should be established at 30 ng/ml, insufficiency between 30 and 20 ng/ml and deficiency low...

Introduction: The risk association between the insulin like growth factor-1 (IGF1) and cardiovascular risk is inconclusive in adults and under-explored in the pediatric population. We aimed to investigate the associations between serum concentrations of IGF1 and cardiovascular risk factors in obese children and adolescents.Methods: Cross-sectional study. Clinical and metabolic evaluations including an oral glucose tolerance test (OGTT) were performed at ...